8-[4-(4-Fluprophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one

CAS: 749-02-0

Ref. 3D-FF27863

Produktinformation

• Name: 8-[4-(4-Fluprophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
• Synonyme: Spiperone4-Phenyl-8-[3-(4-fluorobenzoyl)propyl]-1-oxo-2,4,8-triazaspiro[4,5]decaneSpiropitan, 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-fluorobenzoyl)propyl)-1-phenyl-, 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl-, 8-(3-(p-Fluorobenzoyl)propyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one, 8-(3-p-Fluorobenzoyl-1-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decane, 8-[3-(4-Fluorobenzoyl)propyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]decane, 8-[4-(4-Fluorophenyl)-4-Oxobutyl]-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One, 8-[4-(4-Fluorophenyl)-4-Oxobutyl]-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One Hydrochloride (1:1), Brn 0632204, Butyrophenone, 4'-fluoro-4-(4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decan-8-yl)-, E 525, Espiperona, Espiperona [INN-Spanish], Nsc 170983, R 5147, Spiperon, Spiperone [USAN:INN:BAN:JAN], Spiperonum, Spiperonum [INN-Latin], Spiroperidol, Spiroperidone, Spiropitan, Unii-4X6E73Cj0Q
• CAS: 749-02-0

Beschreibung

8-[4-(4-Fluprophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one (8OHPPD) is a prodrug that is hydrolyzed in vivo to 8-[4-(4-fluorophenyl)-4-oxobutyl]-1,3,8-triazaspiro[4.5]decane (8FBP), its active form. This drug has been shown to be an effective treatment for bowel disease and eye disorders. It activates the 5HT2C receptor in the brain and this activation may be responsible for its beneficial effects on bowel disease. 8OHPPD also has shown anticancer activity against breast cancer cells that express high levels of HER2+ receptors. The drug inhibits dopamine release by binding to 5HT2 receptors and it has been shown to inhibit tumor growth in mouse models of breast cancer

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 395.47 g/mol
• Formel: C₂₃H₂₆FN₃O₂
• Reinheit: Min. 95%
• Farbe/Form: Powder