5'-Fluoro-2'-methoxyacetophenone

CAS: 445-82-9

Ref. 3D-FF43401

Produktinformation

• Name: 5'-Fluoro-2'-methoxyacetophenone
• Synonyme: 1-(5-Fluoro-2-methoxyphenyl)ethanone, Ethanone, 1-(5-fluoro-2-methoxyphenyl)-

Beschreibung

5'-Fluoro-2'-methoxyacetophenone is a reactive intermediate that undergoes an electrophilic aromatic substitution with methanol to form the corresponding fluorinated methoxyacetophenone. It can be used to synthesize other fluorinated compounds.
5'-Fluoro-2'-methoxyacetophenone can be activated by reaction with O-chloro-N,O-dimethylhydroxylamine hydrochloride (O-CDMAH) in acetonitrile at room temperature to form the corresponding chloromethylated product. The activated intermediate is then reacted with methanol in methanol/water (1:4) to yield the desired product.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 168.16 g/mol
• Formel: C₉H₉FO₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C9H9FO2/c1-6(11)8-5-7(10)3-4-9(8)12-2/h3-5H,1-2H3
• InChI Key: InChIKey=CNVGMLMIQIPAFY-UHFFFAOYSA-N
• SMILES: COc1ccc(F)cc1C(C)=O