4-Fluoro-1-cyclohexanecarboxylicacid
CAS: 95233-41-3
Ref. 3D-FF45141
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Produktinformation
Name:
4-Fluoro-1-cyclohexanecarboxylicacid
Beschreibung:
4-Fluoro-1-cyclohexanecarboxylic acid is a serotonin receptor ligand that binds to the 5-HT1A receptor. It is used as a radioligand for positron emission tomography (PET) imaging of the 5-HT1A receptor in animal and human studies. 4-Fluoro-1-cyclohexanecarboxylic acid has been shown to have high affinity for the 5-HT1A receptor, with an intercept of 0.14 nM at the highest concentration tested (100 μM). This drug has been shown to have good pharmacokinetic properties in rats, with a half life of 1.5 hours and a volume of distribution of 2.3 L/kg. 4-Fluoro-1-cyclohexanecarboxylic acid also has biological properties that are not shared by other drugs, including uptake by rat hepatocytes.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
146.16 g/mol
Formel:
C7H11FO2
Reinheit:
Min. 95%
InChl:
InChI=1S/C7H11FO2/c8-6-3-1-5(2-4-6)7(9)10/h5-6H,1-4H2,(H,9,10)
InChI Key:
InChIKey=IUMDEBKXOXPBEX-UHFFFAOYSA-N
SMILES:
O=C(O)C1CCC(F)CC1
MDL:
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