Fmoc-O-benzylphospho-L-threonine

CAS: 175291-56-2

Ref. 3D-FF47778

Produktinformation

• Name: Fmoc-O-benzylphospho-L-threonine
• Synonyme: Fmoc-L-Thr(HPO3Bzl)-OHFmoc-Thr(PO(OBzl)OH)-OH, Fmoc-Thr(HPO3Bzl)-OH, O-[(benzyloxy)(hydroxy)phosphoryl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-threonine, Fmoc-Thr(PO(OBzl))-OH, Fmoc-Thr[PO(OBzl)OH]-OH
• CAS: 175291-56-2

Beschreibung

Fmoc-O-benzylphospho-L-threonine (FMOC-OTP) is a modified amino acid that has been used in research to study the structure and function of nucleic acids. FMOC-OTP can be used to inhibit the activity of p53, which is an important protein involved in cell cycle control and tumor suppression. FMOC-OTP binds to the c-terminal domain of p53, stabilizing it and preventing its degradation. This leads to increased levels of tetramerization and higher affinity for DNA. Studies have shown that FMOC-OTP can be used to stabilize p53 in cells with high levels of damage, such as tumours.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 511.46 g/mol
• Formel: C₂₆H₂₆NO₈P
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Powder