N-alpha-Fmoc-L-asparagine 4-nitrophenyl ester

CAS: 71989-17-8

Ref. 3D-FF48557

Produktinformation

• Name: N-alpha-Fmoc-L-asparagine 4-nitrophenyl ester
• Synonyme: Fmoc-L-Asn-ONp, 4-nitrophenyl N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]asparaginate
• CAS: 71989-17-8

Beschreibung

N-alpha-Fmoc-L-asparagine 4-nitrophenyl ester is an amide that is synthesized from fluorescamine, p-nitrophenyl, and ethyl acetate. It can be used to produce a pentapeptide with the sequence of Gly-Glu-Ala-Gly. This pentapeptide has been shown to have immunosuppressive properties and may be useful in the treatment of inflammatory diseases such as asthma. The pentapeptide is synthesized by reacting 1-hydroxybenzotriazole (HOBt) and diethylamine in dimethylformamide (DMF) to form the tetrapeptide with the sequence of Nα-(1H)-FMOC-[L]-ASP-[Nα]pNP. The monomers are coupled using elemental analysis or ninhydrin or diethylamine for detection.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 475.45 g/mol
• Formel: C₂₅H₂₁N₃O₇
• Reinheit: Min. 95%