5-Fluoroindole-2-carboxylic acid methyl ester

CAS: 167631-84-7

Ref. 3D-FF56772

Produktinformation

• Name: 5-Fluoroindole-2-carboxylic acid methyl ester
• Synonyme: 5-Fluoro-1H-indole-2-carboxylic acid methyl esterMethyl 5-fluoro-1H-indole-2-carboxylate, Cbi-Bb Zero/005614, Methyl 5-Fluoroindole-2-Carboxylate, Akos Jy2083270, 5-Fluoroindole-2-Carboxylic Acid Methyl Ester, methyl 5-fluoro-1H-indole-2-carboxylate
• CAS: 167631-84-7

Beschreibung

5-Fluoroindole-2-carboxylic acid methyl ester (5FCM) is a potent and selective diabetogenic agent that is currently under development for the treatment of type 2 diabetes. 5FCM binds to the active site of pancreatic α-amylase, inhibiting its function and reducing blood glucose levels. It has been shown to have a good safety profile in animal studies. The kinetic parameters for 5FCM are determined by measuring the effect of this drug on pancreatic α-amylase activity. These parameters include the inhibition constant KI, which is an indicator for potency, and the inhibition rate constant kI, which determines how quickly 5FCM inhibits pancreatic α-amylase activity. The interaction between 5FCM and pancreatic α-amylase has been studied using molecular modeling techniques.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 193.17 g/mol
• Formel: C₁₀H₈FNO₂
• Reinheit: Min. 95%