Produktinformation
- 6-Fluoro-1H-quinolin-2-one
- 6-Fluoro-2(1H)-quinolinone
- 6-Fluorocarbostyril
- 6-Fluoroquinolin-2(1H)-one
- Carbostyril, 6-fluoro-
- Carbostyril,6-fluoro- (8CI)
6-Fluoro-2(1H)-Quinolinone is a synthetic compound that inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. It is a fluoroquinolone antibiotic that is used for the treatment of bacterial infections. The molecular modeling of 6-fluoro-2(1H)-quinolinone has shown that it has two methoxy groups on its benzene ring at positions 3 and 4. These methoxy groups are believed to provide additional stability to the molecule in acidic conditions because they form hydrogen bonding interactions with chloride ions. The absorption process of 6-fluoro-2(1H)-quinolinone has been shown to be constant throughout the concentration range studied, which may be due to its amphiphilic nature. The MIC90 values for 6-fluoro-2(1H)-quinolinone have been found to be in the range of 0.5-4 μg/ml against staphyl