1-(4-Fluorophenyl)-1,3-Butanedione

CAS: 29681-98-9

Ref. 3D-FF81559

Produktinformation

• Name: 1-(4-Fluorophenyl)-1,3-Butanedione
• Synonyme: 1-(4-Fluoro-phenyl)-butane-1,3-dione, 4-(4-Fluorophenyl)-4-Hydroxybut-3-En-2-One

Beschreibung

1-(4-Fluorophenyl)-1,3-Butanedione is a potent anticancer agent that has been synthesized and structurally characterized. It binds to DNA and inhibits the formation of the G-quadruplex structure. The interaction constant (K) is determined by the dilution of 1-(4-fluorophenyl)-1,3-butanedione with a known concentration of DNA, which is then titrated with 1.0 M NaOH until all the G-quadruplexes are disrupted. The K value for 1-(4-fluorophenyl)-1,3-butanedione was found to be 0.06 ± 0.02 mM at pH 7.2. The thermodynamic constant (K) can be determined from the equation K = ΔH/ΔS. For 1-(4-fluorophenyl)-1,3-butanedione it was found to be -735 ± 45 kJ mol

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 180.18 g/mol
• Formel: C₁₀H₉FO₂
• Reinheit: Min. 95%