N-(7-Fluoro-9H-Fluoren-2-Yl)-N-Hydroxyacetamide

Ref. 3D-FF90283

Produktinformation

• Name: N-(7-Fluoro-9H-Fluoren-2-Yl)-N-Hydroxyacetamide
• Marke: Biosynth
• Beschreibung: N-(7-Fluoro-9H-Fluoren-2-Yl)-N-Hydroxyacetamide is a metabolite of fluoroacetamide. It is a carcinogenic agent that is used in the metabolism of 3-methylcholanthrene and 2-aminofluorene. This compound catalyzes the formation of reactive oxygen species, which results in DNA damage and mutation. Pretreatment with N-(7-fluoro-9H-fluoren-2yl)-N hydroxyacetamide reduces the carcinogenic effect of 8hydroxyquinoline on liver microsomes in rats. This drug also causes hepatocarcinogenesis in mice when administered at high doses over a long period of time.

Chemische Eigenschaften

• Molekulargewicht: 257.26 g/mol
• Formel: C₁₅H₁₂FNO₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C15H12FNO2/c1-9(18)17(19)13-3-5-15-11(8-13)6-10-7-12(16)2-4-14(10)15/h2-5,7-8,19H,6H2,1H3
• InChI Key: InChIKey=UAUQZGBNJDVZJI-UHFFFAOYSA-N
• SMILES: CC(=O)N(O)c1ccc2c(c1)Cc1cc(F)ccc1-2