6-Oxo simvastatin

CAS: 130468-11-0

Ref. 3D-FFA46811

Produktinformation

• Name: 6-Oxo simvastatin
• CAS: 130468-11-0

Beschreibung

6-Oxo simvastatin is a homolog of the cholesterol synthesis inhibitor simvastatin. It inhibits the enzyme HMG-CoA reductase, which is involved in the production of cholesterol. 6-Oxo simvastatin can be extracted from microbial cultures and has been shown to inhibit microbial transformation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) into mevalonic acid during growth. 6-Oxo simvastatin has been shown to have potent inhibitory effects on HMG CoA reductase in subspecies that are resistant to other inhibitors such as lovastatin and pravastatin.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 432.5 g/mol
• Formel: C₂₅H₃₆O₆
• Reinheit: Min. 95%