HBTU

CAS: 94790-37-1

Ref. 3D-FH07095

Produktinformation

• Name: HBTU
• Synonyme: N,N,N',N'-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphateO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
• Marke: Biosynth
• Beschreibung: HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Chemische Eigenschaften

• Molekulargewicht: 379.24 g/mol
• Formel: C₁₁H₁₆F₆N₅OP
• Reinheit: Min. 99 Area-%
• Farbe/Form: White Powder