2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride

CAS: 62732-44-9

Ref. 3D-FH133264

Produktinformation

• Name: 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride
• Synonyme: 1H-cyclopenta[b]quinolin-9-amine, 2,3,5,6,7,8-hexahydro-, hydrochloride, 1H,2H,3H,5H,6H,7H,8H-Cyclopenta[b]quinolin-9-amine, 1H-Cyclopenta[b]quinolin-9-amine, 2,3,5,6,7,8-hexahydro-, 2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-ylamine, 9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinoline, Ipidacrine, Neuromidine

Beschreibung

2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride (HCPQ) is a potent and selective inhibitor of the enzyme DPP-IV. HCPQ has been shown to reduce symptoms of type 2 diabetes by lowering glucose levels in the blood. The drug also inhibits cholinergic neurotransmission and may be used for the treatment of Alzheimer's disease and diabetic neuropathy. HCPQ binds to the catalytic site of DPP-IV and prevents it from breaking down an important signaling molecule called incretin insulin. This leads to an increase in intracellular calcium levels which can activate proteins involved in energy metabolism. HCPQ also inhibits acetylcholinesterase activity which may lead to neuronal death in Alzheimer's disease patients.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 188.27 g/mol
• Formel: C₁₂H₁₆N₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C12H16N2/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12/h1-7H2,(H2,13,14)
• InChI Key: InChIKey=YLUSMKAJIQOXPV-UHFFFAOYSA-N
• SMILES: Nc1c2c(nc3c1CCC3)CCCC2