HOTT

CAS: 212333-72-7

Ref. 3D-FH15658

Produktinformation

• Name: HOTT
• Synonyme: N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphateS-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuronium hexa fluorophosphateS-(2-Pyridyl)-N,N,N',N'-tetramethylthiuronium N-oxide hexafluorophosphate, Hott, N-{(dimethylamino)[(1-oxidopyridin-2-yl)sulfanyl]methylidene}-N-methylmethanaminium hexafluorophosphate

Beschreibung

HOTT is a uronium salt used as a coupling reagent in the synthesis of peptides, primary amides, hydroxamates, Weinreb amides and Barton esters. HOTT is used in presence of Hünig's base, is soluble in DMF, finds application in solid phase and in solution synthesis and achieves high yields with low levels of racemisation, at an affordable cost. HOTT can form labile Barton esters in the presence of triethylamine afrom hindered or difficult carboxylic acids.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 371.28 g/mol
• Formel: C₁₀H₁₆N₃OS•F₆P
• Reinheit: Min. 95%
• Farbe/Form: White/Off-White Solid