Vorinostat

CAS: 149647-78-9

Ref. 3D-FH15949

Produktinformation

• Name: Vorinostat
• Synonyme: N-Hydroxy-N'-phenyl-octanediamide Suberoylanilide hydroxamic acid SAHA, Ccris 8456, M344, N-Hydroxy-N'-phenyloctanediamide, N-Hyrdroxy-N'-phenyloctanediamide, N¹-Hydroxy-N⁸-phenyloctanediamide, Octanediamide, N-hydroxy-N'-phenyl-, Octanediamide, N¹-hydroxy-N⁸-phenyl-, SAHA cpd, Suberanilohydroxamic acid, Suberoyl anilide bishydroxamide, Suberoylanilide Hydroxamic Acid, Unii-58Ifb293Ji, Vorinostat [USAN], Wt 171, Zolinza, Octanediamide, N1-hydroxy-N8-phenyl-, SAHA, N1-Hydroxy-N8-phenyloctanediamide

Beschreibung

Vorinostat is a histone deacetylase inhibitor which interferes with gene transcription regulatory mechanisms. It targets histones and non-histone proteins within transcription factor complexes involved in regulation of cell proliferation (p53), protein stability (Hsp90), apoptosis (Bcl-2 family), cell motility (α-tublin), and angiogenesis (HIF-1α). Vorinostat affects epigenetic regulation in various cancers and has been used in clinical trials as anticancer drug.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 264.32 g/mol
• Formel: C₁₄H₂₀N₂O₃
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Powder