Voxelotor

CAS: 1446321-46-5

Ref. 3D-FH167609

Produktinformation

• Name: Voxelotor
• Synonyme: GBT 4402-Hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]benzaldehyde
• Marke: Biosynth
• Beschreibung: Voxelotor is an oral therapeutic agent, which is a small molecule obtained through synthetic chemistry with targeted activity on hemoglobin. Its mode of action involves the allosteric modification of hemoglobin, specifically increasing hemoglobin oxygen affinity. By stabilizing the oxygenated hemoglobin state, voxelotor reduces the sickling and polymerization of red blood cells that are characteristic of sickle cell disease (SCD).

Chemische Eigenschaften

• Molekulargewicht: 337.37 g/mol
• Formel: C₁₉H₁₉N₃O₃
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Powder
• InChl: InChI=1S/C19H19N3O3/c1-13(2)22-16(8-10-21-22)19-14(5-4-9-20-19)12-25-18-7-3-6-17(24)15(18)11-23/h3-11,13,24H,12H2,1-2H3
• InChI Key: InChIKey=FWCVZAQENIZVMY-UHFFFAOYSA-N
• SMILES: CC(C)n1nccc1-c1ncccc1COc1cccc(O)c1C=O