2-Hydroxy atorvastatin-d5 disodium salt
CAS: 1276537-19-9
Ref. 3D-FH174865
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Produktinformation
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-(phenyl-2,3,4,5,6-d5)-, sodium salt (1:2), (βR,δR)-
2-Hydroxy atorvastatin-d5 disodium salt is a statin that inhibits the enzyme HMG-CoA reductase. It has been shown to reduce cholesterol levels in plasma samples, which may be due to its ability to inhibit the 4-hydroxylase activity of this enzyme. 2-Hydroxy atorvastatin-d5 disodium salt also reduces the amount of low density lipoprotein (LDL) cholesterol in plasma. This drug has a linear range from 0.1 to 100 μM and can be used for microdosing experiments with a microdose of 1 μM. 2-Hydroxy atorvastatin-d5 disodium salt can also be used for reversed phase assays with an assay development time of about two hours. The assay can be developed by adding water and acetonitrile to the sample in a ratio of 3:2. Electrospray ionization is then used to generate ions