Produktinformation
- (3aS)-3,3aalpha,4alpha,4a,7aalpha,8,9,9aalpha-Octahydro-4-hydroxy-4abeta,8 alpha-dimethyl-3-methyleneazuleno(6,5-b)-furan-2,5-dione
- (3aS,4S,4aR,7aR,8R,9aR)-3,3a,4,4a,7a,8,9,9a-Octahydro-4-hydroxy-4a,8-dimethyl-3-methyleneazuleno[6,5-b]furan-2,5-dione
- (3aS,4S,4aR,7aR,8R,9aR)-4-hydroxy-4a,8-dimethyl-3-methylidene-3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione
- 6alpha,8beta-Dihydroxy-4-oxoambrosa-2,11(13)-dien-12-oic acid 12,8-lactone
- Ambrosa-2,11(13)-dien-12-oic acid, 6-alpha,8-beta-dihydroxy-4-oxo-, 12,8-lactone
- Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone
- Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone (8CI)
- Ambrosa-2,11(13)-dien-12-oic acid, 6α,8β-dihydroxy-4-oxo-, 12,8-lactone
- Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))-
- Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))- (9CI)
- Mehr Synonyme anzeigen
- Azuleno[6,5-b]furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS,4S,4aR,7aR,8R,9aR)-
- Azuleno[6,5-b]furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, [3aS-(3aα,4α,4aβ,7aα,8α,9aα)]-
- Brn 0028081
- Helenalin A
- Hsdb 3490
- Nsc 85236
- Pf 56
- 4-18-00-01434 (Beilstein Handbook Reference)
Helenalin is a natural compound that belongs to the group of nonsteroidal anti-inflammatory drugs. It has been shown to inhibit 3t3-l1 preadipocytes differentiation and promote apoptosis by inhibiting the phosphorylation of c-jun, as well as decreasing the expression of Mcl-1 protein. Helenalin also inhibits NF-κB binding activity and suppresses the transcriptional factor nuclear factor kappa B (NF-κB) in a dose dependent manner. The antitumor activity of helenalin has been shown to be due to its ability to inhibit cyclin D2 expression, which prevents tumor cell proliferation.
Chemische Eigenschaften
Technische Anfrage zu: 3D-FH177939 Helenalin
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