2-Hydroxy desipramine

CAS: 1977-15-7

Ref. 3D-FH23973

Produktinformation

• Name: 2-Hydroxy desipramine
• Synonyme: 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepin-2-ol2-Hydroxydemethylimipramine2-Hydroxydesmethylimipramine, 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepin-2-ol, 2-Hydroxydemethylimipramine, 2-Hydroxydesipramine, 2-Hydroxydesmethylimipramine, 5-[3-(methylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepin-2-ol, 5H-Dibenz[b,f]azepin-2-ol, 10,11-dihydro-5-[3-(methylamino)propyl]-, Gp 36329

Beschreibung

2-Hydroxy desipramine is a metabolite of desipramine, an antidepressant drug. It is formed from the hydrolysis of desipramine by liver enzymes and is excreted in urine. 2-Hydroxy desipramine has shown to have dose-dependent effects on cardiac function and has been shown to decrease blood pressure in rats. 2-Hydroxy desipramine has been shown to be clinically relevant for patients who are also taking carbamazepine, which can cause an increase in 2-hydroxydesipranime plasma levels. This drug may also interfere with other drugs that are metabolized through glucuronidation pathways.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 282.38 g/mol
• Formel: C₁₈H₂₂N₂O
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C18H22N2O/c1-19-11-4-12-20-17-6-3-2-5-14(17)7-8-15-13-16(21)9-10-18(15)20/h2-3,5-6,9-10,13,19,21H,4,7-8,11-12H2,1H3
• InChI Key: InChIKey=NVJBOLMRGMDGLD-UHFFFAOYSA-N
• SMILES: CNCCCN1c2ccccc2CCc2cc(O)ccc21