4-Hydroxy estrone

CAS: 3131-23-5

Ref. 3D-FH23995

Produktinformation

• Name: 4-Hydroxy estrone
• Synonyme: 1,3,5(10)-Estratriene-3,4-diol-17-one3,4-Dihydroxy-1,3,5(10)-estratrien-17-one
• CAS: 3131-23-5

Beschreibung

4-Hydroxy estrone is a metabolite of estrone. It has been shown to have genotoxic activity, which is thought to be due to its ability to form DNA adducts. 4-Hydroxy estrone has also been found to cause cancer in rat liver microsomes and body mass index in female rats. 4-Hydroxy estrone can be found in the environment as a result of wastewater treatment, where it reacts with triclosan and other compounds. 4-Hydroxy estrone has been shown to inhibit the activity of enzymes such as cytochrome P450 and aromatase that are involved in estrogen metabolism. Tumour necrosis factor-α (TNF-α) stimulates the production of this compound, which is thought to play an important role in the development of obesity-related cancers.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 286.37 g/mol
• Formel: C₁₈H₂₂O₃
• Reinheit: Min. 95%
• Farbe/Form: White To Yellow Or Light (Or Pale) Brown Solid