2-Hydroxy imipramine

CAS: 303-70-8

Ref. 3D-FH24021

Produktinformation

• Name: 2-Hydroxy imipramine
• Synonyme: 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepin-2-ol2-HydroxyimipramineG 33679, 5H-Dibenz[b,f]azepin-2-ol, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepin-2-ol, G 33679, 2-Hydroxyimipramine

Beschreibung

2-Hydroxy imipramine is a metabolite of imipramine, which is an antidepressant drug that belongs to the tricyclic antidepressant class. It is formed through enzyme hydrolysis by liver microsomes and monoclonal antibodies. 2-Hydroxy imipramine has been shown to have an affinity for the norepinephrine transporter in rat heart cells and human liver cells. The metabolism of 2-hydroxy imipramine can be inhibited by drugs such as chlorpromazine and fluoxetine, which induce hepatic enzymes responsible for the metabolic transformation of this drug. 2-Hydroxy imipramine may also have anti-inflammatory effects on cardiac tissue due to its ability to inhibit the activity of cytochrome P450, which are enzymes that metabolize many drugs in humans.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 296.41 g/mol
• Formel: C₁₉H₂₄N₂O
• Reinheit: (%) Min. 95%
• Farbe/Form: Brown Powder
• InChl: InChI=1S/C19H24N2O/c1-20(2)12-5-13-21-18-7-4-3-6-15(18)8-9-16-14-17(22)10-11-19(16)21/h3-4,6-7,10-11,14,22H,5,8-9,12-13H2,1-2H3
• InChI Key: InChIKey=ROTCPJFWLNDKHU-UHFFFAOYSA-N
• SMILES: CN(C)CCCN1c2ccccc2CCc2cc(O)ccc21