8-Hydroxy loxapine

CAS: 61443-77-4

Ref. 3D-FH24034

Produktinformation

• Name: 8-Hydroxy loxapine
• Synonyme: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepin-8-ol, 2-Chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]oxazepin-8-ol, Dibenz(b,f)(1,4)oxazepin-8-ol, 2-chloro-11-(4-methyl-1-piperazinyl)-
• CAS: 61443-77-4

Beschreibung

8-Hydroxy loxapine is a drug that is used as an antipsychotic. It binds to the dopamine receptor in the brain and blocks its activity, which can lead to relief of some symptoms of schizophrenia. 8-Hydroxy loxapine has been shown to be effective against anesthetized rats, with a terminal half-life of about 1 hour. In clinical trials, this drug has been shown to have a good response in patients with Parkinson's disease and other extrapyramidal disorders. 8-Hydroxy loxapine is metabolized into an n-oxide in the liver and it binds to polymerase chain reaction (PCR) primers during bioanalysis. This drug also has regulatory approval for use as a nasal spray for treatment of agitation in elderly patients with dementia who are nonverbal or minimally verbal.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 343.81 g/mol
• Formel: C₁₈H₁₈ClN₃O₂
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C18H18ClN3O2/c1-21-6-8-22(9-7-21)18-14-10-12(19)2-4-16(14)24-17-5-3-13(23)11-15(17)20-18/h2-5,10-11,23H,6-9H2,1H3
• InChI Key: InChIKey=VNJRIWXLPIYFGI-UHFFFAOYSA-N
• SMILES: CN1CCN(C2=Nc3cc(O)ccc3Oc3ccc(Cl)cc32)CC1