3a-Hydroxy pravastatin lactone

CAS: 85798-96-5

Ref. 3D-FH24091

Produktinformation

• Name: 3a-Hydroxy pravastatin lactone
• Synonyme: 3a-iso-Pravastatin(2S)-2-Methylbutanoic acid (1S,6S,7R,8S,8aR)-1,2,6,7,8,8a-hexahydro-6-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4 -hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl esterSQ 31906 lactone, Butanoic acid, 2-methyl-, 1,2,6,7,8,8a-hexahydro-6-hydroxy-7-methyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester

Beschreibung

3a-Hydroxy pravastatin lactone is a nitrile that is used as a remedy. It has been shown to decrease the levels of serum cholesterol and triglycerides in hyperlipemic animals. This drug also inhibits microbial growth, with the exception of gram-positive bacteria. 3a-Hydroxy pravastatin lactone is metabolized in the liver by transformation to 3a-hydroxypravastatin, which is then excreted in bile and urine. The transformation process can be inhibited by sulfuric acid or hydrochloric acid. 3a-Hydroxy pravastatin lactone has also been shown to have anti-inflammatory properties (e.g., inhibition of COX activity) and can inhibit arteriosclerosis due to its ability to inhibit lipoprotein lipase and hepatic HMG CoA reductase activity.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 406.51 g/mol
• Formel: C₂₃H₃₄O₆
• Reinheit: Min. 95%