6-Hydroxy-2-naphthaleneacetic acid
CAS: 10441-46-0
Ref. 3D-FH24205
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Produktinformation
Name:
6-Hydroxy-2-naphthaleneacetic acid
Synonyme:
- 2-(6-Hydroxynaphthalen-2-yl)acetic acid
- 2-Naphthaleneacetic acid, 6-hydroxy-
Beschreibung:
6-Hydroxy-2-naphthaleneacetic acid (6HNA) is a nonsteroidal anti-inflammatory drug that acts as an inhibitor of prostaglandin synthesis. It has been shown to inhibit the production of prostaglandins by rat liver microsomes, and is metabolized through a series of reactions involving reduction products, glucuronidation, and conjugation with glutathione. 6HNA has been shown to be orally active in rats and mice, but has not been tested in humans. It is also used as a substrate for the recombinant human β-glucuronidase enzyme in kinetic studies on the metabolism of xenobiotics.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
202.21 g/mol
Formel:
C12H10O3
Reinheit:
Min. 95%
InChl:
InChI=1S/C12H10O3/c13-11-4-3-9-5-8(6-12(14)15)1-2-10(9)7-11/h1-5,7,13H,6H2,(H,14,15)
InChI Key:
InChIKey=YNECZMXVHIGGSP-UHFFFAOYSA-N
SMILES:
O=C(O)Cc1ccc2cc(O)ccc2c1
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