N-Hydroxymaleimide

CAS: 4814-74-8

Ref. 3D-FH24382

Produktinformation

• Name: N-Hydroxymaleimide
• Synonyme: N-Hydroxymaleamine1-Hydroxy-2,5-dihydro-1H-pyrrole-2,5-dione, 1-Hydroxy-2,5-dihydro-1H-pyrrole-2,5-dione, 1-Hydroxypyrrole-2,5-dione, 1H-Pyrrole-2,5-dione, 1-hydroxy-, Maleimide, N-hydroxy-

Beschreibung

N-Hydroxymaleimide is a reactive amide that is used as an oxidation catalyst in the synthesis of monoclonal antibodies. It is also used in the preparation of conjugates for immunological assays. N-Hydroxymaleimide is typically synthesized by liquid phase methods, which are more efficient than solid phase methods. The reaction proceeds through the dehydration of an amine with a primary or secondary alcohol to form an amide. This process is irreversible and must be carried out under mild conditions to avoid side reactions with functional groups on the reactants. N-Hydroxymaleimide can be purified by gel chromatography methods before use, but it cannot be stored for long periods because it reacts with water, trifluoroacetic acid, and many other substances.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 113.07 g/mol
• Formel: C₄H₃NO₃
• Reinheit: Min. 95%
• Farbe/Form: Off-White Powder