N-alpha-Z-L-histidine

CAS: 14997-58-1

Ref. 3D-FH47279

Produktinformation

• Name: N-alpha-Z-L-histidine
• Synonyme: Z-L-His-OH
• Marke: Biosynth

Beschreibung

N-alpha-Z-L-histidine is a nitrogenous compound that is an amide formed by the reaction of histidine and trifluoroacetic acid. It has been shown to be anticancer and to have an effect on tumor vasculature, with efficacy against solid tumors. N-alpha-Z-L-histidine inhibits the cell cycle at the G1 phase and blocks DNA synthesis, which arrests cells in the M phase. This drug also inhibits tumor angiogenesis by blocking vascular endothelial growth factor (VEGF) signaling. N-alpha-Z-L-histidine is a molecule that has been synthesized using solid phase chemistry and purified by high performance liquid chromatography.

Chemische Eigenschaften

• Molekulargewicht: 289.29 g/mol
• Formel: C₁₄H₁₅N₃O₄
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C14H15N3O4/c18-13(19)12(6-11-7-15-9-16-11)17-14(20)21-8-10-4-2-1-3-5-10/h1-5,7,9,12H,6,8H2,(H,15,16)(H,17,20)(H,18,19)/t12-/m0/s1
• InChI Key: InChIKey=WCOJOHPAKJFUDF-LBPRGKRZSA-N
• SMILES: O=C(N[C@@H](Cc1cnc[nH]1)C(=O)O)OCc1ccccc1