2-Hydroxyisonicotinic acid

CAS: 22282-72-0

Ref. 3D-FH50815

Produktinformation

• Name: 2-Hydroxyisonicotinic acid
• Synonyme: 2-Hydroxy-4-pyridinecarboxylic acid4-Carboxy-2(1H)-pyridinone
• Marke: Biosynth
• Beschreibung: 2-Hydroxyisonicotinic acid is a synthetic analog of isonicotinic acid that is used as a nonheme iron chelator. It has been shown to inhibit the growth of cavity-causing bacteria in vitro by binding to iron enzymes, such as methane monooxygenase and n-oxide reductase. 2-Hydroxyisonicotinic acid inhibits bacterial growth by binding to the enzyme complexes containing iron, thereby inhibiting the synthesis of fatty acids and pyridine compounds. X-ray crystal structures have also shown that this compound binds to the nonheme iron at two sites, which may explain its ability to inhibit bacterial growth.

Chemische Eigenschaften

• Molekulargewicht: 139.11 g/mol
• Formel: C₆H₅NO₃
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C6H5NO3/c8-5-3-4(6(9)10)1-2-7-5/h1-3H,(H,7,8)(H,9,10)
• InChI Key: InChIKey=BXHCJLRTXPHUGH-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc[nH]c(=O)c1