Hypaphorine

CAS: 487-58-1

Ref. 3D-FH74222

Produktinformation

• Name: Hypaphorine
• Synonyme: Tryptophan betaine, 1H-Indole-3-ethanaminium, α-carboxy-N,N,N-trimethyl-, inner salt, (αS)-, (1-Carboxy-2-indol-3-ylethyl)trimethylammonium hydroxide, inner salt, Ammonium, (1-carboxy-2-indol-3-ylethyl)trimethyl-, hydroxide, inner salt, 1H-Indole-3-ethanaminium, α-carboxy-N,N,N-trimethyl-, inner salt, (S)-

Beschreibung

Hypaphorine is a protein that is a chemoattractant for neutrophils, monocytes, and lymphocytes. It also has biological properties that are similar to those of the neurotransmitter histamine. Hypaphorine is found in increased quantities in the plasma of obese individuals and may be involved in obesity-related inflammation. In vitro studies show that hypaphorine increases cytosolic calcium concentrations and activates toll-like receptor 2 (TLR2). TLR2 is an immune system receptor that binds to bacterial DNA or RNA to initiate an inflammatory response. Hypaphorine is also able to inhibit the activity of enzymes involved in lipid metabolism such as 3t3-l1 preadipocytes and reduce atherosclerosis in vivo.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 246.31 g/mol
• Formel: C₁₄H₁₈N₂O₂
• Reinheit: Min. 95%
• Farbe/Form: White Powder