5-Iodocytosine

CAS: 1122-44-7

Ref. 3D-FI08021

Produktinformation

• Name: 5-Iodocytosine
• Synonyme: 4-Amino-2-hydroxy-5-iodopyrimidine6-Amino-5-iodopyrimidin-2(1H)-one, 2(1H)-Pyrimidinone, 4-amino-5-iodo-, 2(1H)-Pyrimidinone, 6-amino-5-iodo-, 4-Amino-5-iodo-2(1H)-pyrimidinone, 6-Amino-5-iodo-2(1H)-pyrimidinone, 6-amino-5-iodopyrimidin-2(1H)-one, Cytosine, 5-iodo-

Beschreibung

5-Iodocytosine (5-IC) is an analog of cytosine that can be used as a precursor for the synthesis of thymine. 5-IC has been shown to cross-couple with DNA, which may contribute to its antiviral potency. 5-IC is also a potent inhibitor of dna replication and herpes simplex virus. The biochemical properties of 5-IC have been extensively studied, including its ability to react with hydrochloric acid to form the corresponding tautomers. The hydrolysis rate increases at higher pH values and decreases at lower pH values. Bioconjugate chemistry has been applied to synthesize a bioconjugated prodrug of 5-IC for cancer treatment.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 237 g/mol
• Formel: C₄H₄IN₃O
• Reinheit: Min. 95%
• Farbe/Form: Powder