Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde

CAS: 158442-41-2

Ref. 3D-FI111570

Produktinformation

• Name: Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde
• Synonyme: PSI, Proteasome Inhibitor I
• CAS: 158442-41-2

Beschreibung

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde, also known as ZILEAL, is a potent immunosuppressant that binds to the Toll-like receptor (TLR) and inhibits NF-κB binding activity. It has been shown to reduce the activation of macrophages by inhibiting the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNFα), IL-1β, and IL-6. This drug has been shown to inhibit HIV replication in vitro and was also found to have an antiviral effect against herpes simplex virus type 1 in vivo. ZILEAL also inhibits dsDNA binding activity, which may have potential applications in cancer treatment.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 618.76 g/mol
• Formel: C₃₂H₅₀N₄O₈
• Reinheit: Min. 95%