5-Iodo-7H-pyrrolo[2,3-d]pyrimidine

CAS: 175791-53-4

Ref. 3D-FI154981

Produktinformation

• Name: 5-Iodo-7H-pyrrolo[2,3-d]pyrimidine

Beschreibung

5-Iodo-7H-pyrrolo[2,3-d]pyrimidine is a palladium-catalyzed cross-coupling reaction that can be used to synthesize 5-(iodomethyl)benzofuran. The palladium catalyst is generated in situ from the reaction of palladium chloride and triethylamine. The reaction uses a Suzuki coupling with 2 molar equivalents of 7H-pyrrolo[2,3-d]pyrimidine and 1 equivalent of phenylboronic acid. It proceeds via an oxidative addition followed by reductive elimination. The product is purified by column chromatography using silica gel as the stationary phase.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 245.02 g/mol
• Formel: C₆H₄IN₃
• Reinheit: Min. 95%