1H-Indazol-3-ylamine

Ref. 3D-FI16217

Produktinformation

• Name: 1H-Indazol-3-ylamine
• Marke: Biosynth
• Beschreibung: 1H-Indazol-3-ylamine is a novel drug that has been shown to inhibit the Abl kinase. The drug binds to the ATP binding site at the N-terminus of the kinase and prevents ATP from activating the kinase. It also inhibits the phosphorylation of Bcr-Abl, which is essential for its growth and survival. 1H-Indazol-3-ylamine has been shown to be active against cells with a high level of bcr-abl kinase activity, such as K562 leukemia cells, in transfection experiments. This drug also inhibits Bcr-Abl tyrosine phosphorylation and blocks signals downstream of Bcr-Abl, such as protein synthesis and cell division.; 1H-Indazol-3-ylamine has been found to have potential anticancer activity against atherosclerotic cardiovascular disease (CVD) in mice models by inhibiting lipid accumulation in

Chemische Eigenschaften

• Molekulargewicht: 133.15 g/mol
• Formel: C₇H₇N₃
• Reinheit: Min. 95%