Indole-3-glyoxylamide

CAS: 5548-10-7

Ref. 3D-FI30472

Produktinformation

• Name: Indole-3-glyoxylamide
• Synonyme: 1H-Indole-3-acetamide, alpha-oxo-, Nsc 56129, alpha-Oxo-1H-indole-3-acetamide

Beschreibung

Indole-3-glyoxylamide is a synthetic compound that was originally developed as a potential anti-cancer drug. It has been shown to inhibit glycogen synthase kinase 3 (GSK-3) and thereby reduce the production of proinflammatory cytokines in bowel disease. Indole-3-glyoxylamide also inhibits inflammatory bowel disease by inhibiting secretory phospholipase A2, which prevents the release of arachidonic acid from phospholipids. This synthesis is required for the production of prostaglandins and leukotrienes, which are involved in the inflammatory process. The compound has been shown to have immunomodulatory effects in chronic bronchitis, with an inhibitory effect on neutrophil chemotaxis, macrophage activity, and cytokine production. Indole-3-glyoxylamide has also been shown to be effective against cancer cells in vitro and in vivo animal models. It is metabolized through

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 188.18 g/mol
• Formel: C₁₀H₈N₂O₂
• Reinheit: Min. 95%
• Farbe/Form: Powder