Produktinformation
- 9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinoline hydrochloride monohydrate
- Ipidacrine hydrochloride hydrate
- 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate
Ipidacine hydrochloride hydrate is a natural product that belongs to the class of organic acids. It is found in the cavity of plants and has been used as a herb to treat diabetes and neuropathic pain. Ipidacine hydrochloride hydrate has been shown to inhibit microbial growth by inhibiting fatty acid synthesis. The inhibition of fatty acid synthesis leads to a decrease in the amount of energy available for cell growth and reproduction, which causes microbial death. Ipidacine hydrochloride hydrate also inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ipidacine hydrochloride hydrate was identified in a model system using ganoderma lucid
