Isoalantolactone

CAS: 470-17-7

Ref. 3D-FI32778

Produktinformation

• Name: Isoalantolactone
• Synonyme: Isohelenin, (3Ar,4As,8Ar,9Ar)-8A-Methyl-3,5-Dimethylene-Decahydro-Naphtho[2,3-B]Furan-2-One, (3aR,4aS,8aR,9aR)-8a-methyl-3,5-dimethylidenedecahydronaphtho[2,3-b]furan-2(3H)-one, (3aR,4aS,8aR,9aR)-Decahydro-8a-methyl-3,5-bis(methylene)naphtho[2,3-b]furan-2(3H)-one, 5αH-Eudesma-4(15),11(13)-dien-12,8β-olide, Eudesma-4(14),11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone, Isoallantolactone, NSC 241036, Naphtho[2,3-b]furan-2(3H)-one, decahydro-8a-methyl-3,5-bis(methylene)-, (3aR,4aS,8aR,9aR)-, Naphtho[2,3-b]furan-2(3H)-one, decahydro-8a-methyl-3,5-bis(methylene)-, [3aR-(3aα,4aα,8aβ,9aα)]-

Beschreibung

Isoalantolactone is a natural compound that has been shown to have pro-apoptotic properties in 3T3-L1 preadipocytes and HL-60 cells. It binds to the dna binding activity of p53, which regulates apoptosis. Isoalantolactone also inhibits NF-κB binding activity and inhibits tubulointerstitial injury in rats with cyclosporin A induced nephropathy. Isoalantolactone can be used as an anti-inflammatory agent, due to its ability to inhibit the activation of NF-κB. The molecular pathogenesis of this drug is not well understood at this time.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 232.32 g/mol
• Formel: C₁₅H₂₀O₂
• Reinheit: Min. 97 Area-%
• Farbe/Form: White Powder