1H-Indole-3-carboxylic acid amide

CAS: 1670-85-5

Ref. 3D-FI34040

Produktinformation

• Name: 1H-Indole-3-carboxylic acid amide

Beschreibung

1H-Indole-3-carboxylic acid amide is an indole derivative with potent inhibitory activity against cancer cells. It is a potent inhibitor of hepg2 cell growth and is able to induce apoptosis. This compound has been shown to have pharmacokinetic properties including oral bioavailability, plasma protein binding, and metabolic stability. 1H-Indole-3-carboxylic acid amide binds to the CB2 receptor and inhibits the release of proinflammatory cytokines. It also has an intramolecular hydrogen bond which may contribute to its potency as a therapeutic agent. 1H-Indole-3-carboxylic acid amide crystallizes in two different polymorphs: one with nitrogen atoms in a trans configuration and one with nitrogen atoms in a cis configuration.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 160.17 g/mol
• Formel: C₉H₈ON₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C9H8N2O/c10-9(12)7-5-11-8-4-2-1-3-6(7)8/h1-5,11H,(H2,10,12)
• InChI Key: InChIKey=LSGKMZLPZFPAIN-UHFFFAOYSA-N
• SMILES: NC(=O)c1c[nH]c2ccccc12