Indobufen

CAS: 63610-08-2

Ref. 3D-FI37690

Produktinformation

• Name: Indobufen
• Synonyme: (2R)-2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid, 1-Oxo-2-[p-[(α-ethyl)carboxymethyl]phenyl]isoindoline, 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid, 2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid, 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric acid, 4-(1,3-Dihydro-1-oxo-(2H)-isoindol-2-yl)-alpha-ethylbenzeneacetic acid, 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid, Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-, Ibustrin, K 2930, K 3920

Beschreibung

Indobufen is a drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to be effective in treating infectious diseases, including malaria and bacterial infections. Indobufen has been shown to inhibit the production of prostaglandin E2 (PGE2) in an experimental model at low doses. This inhibition leads to reduced levels of PGE2 receptor activity and decreased enzyme activities such as cyclooxygenase and lipoxygenase, which are involved in inflammation. This drug also inhibits platelet aggregation and increases bleeding time. The effects of indobufen on human pharmacokinetics have been studied using human serum and platelet samples from healthy volunteers. Indobufen is rapidly absorbed, with a half-life of 1 hour, and it is metabolized by cytochrome P450 (CYP450). Indobufen has also been shown to increase cardiac contractility without affecting heart rate or blood pressure levels.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 295.33 g/mol
• Formel: C₁₈H₁₇NO₃
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)
• InChI Key: InChIKey=AYDXAULLCROVIT-UHFFFAOYSA-N
• SMILES: CCC(C(=O)O)c1ccc(N2Cc3ccccc3C2=O)cc1