(Lys8-psi(CH2NH)Lys9)-Neurotensin (8-13)

CAS: 139026-66-7

Ref. 3D-FL110306

Produktinformation

• Name: (Lys8-psi(CH2NH)Lys9)-Neurotensin (8-13)
• Synonyme: H-Lys-psi(CH2NH)Lys-Pro-Tyr-Ile-Leu-OH, [Lys8-Psi(Ch2Nh)-Lys9]Neurotensin (8-13), (Lys8-(R)-Lys9)-Neurotensin (8-13), Lys-Psi(Ch2Nh)-Lys-Pro-Tyr-Ile-Leu, H-Lys-(R)-Lys-Pro-Tyr-Ile-Leu-Oh, M.W. 746.96 C38H66N8O7, N~2~-[(2S)-2,6-diaminohexyl]-L-lysyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine

Beschreibung

Neurotensin (NT) is a neuropeptide that is derived from the prepro-NT gene. It binds to the neurotensin receptor 1 (NTSR1) and has been shown to regulate intestinal motility, as well as function as an adjuvant therapy for enteric diseases. Neurotensin has been shown to be neuroprotective against dopamine toxicity in cell cultures, and could be used in cancer therapy. The profile of neurotensin has been studied in clinical trials for metastatic breast cancer and other cancers. Neurotensin does not have any significant safety issues, although it can cause neuronal death when administered intracerebroventricularly.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 746.98 g/mol
• Formel: C₃₈H₆₆N₈O₇
• Reinheit: Min. 95%
• InChl: InChI=1S/C38H66N8O7/c1-5-25(4)33(36(50)44-31(38(52)53)21-24(2)3)45-34(48)30(22-26-14-16-28(47)17-15-26)43-35(49)32-13-10-20-46(32)37(51)29(12-7-9-19-40)42-23-27(41)11-6-8-18-39/h14-17,24-25,27,29-33,42,47H,5-13,18-23,39-41H2,1-4H3,(H,43,49)(H,44,50)(H,45,48)(H,52,53)/t25-,27-,29-,30-,31-,32-,33-/m0/s1
• InChI Key: InChIKey=TZCYVPLNMOJUIL-GULBXNHPSA-N
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O