Produktinformation
Name:Linderalactone
Marke:Biosynth
Beschreibung:Linderalactone is a sesquiterpene lactone that inhibits the cell cycle and induces apoptosis. It inhibits the expression of p21, which is an inhibitor of cyclin-dependent kinases and is involved in the regulation of cell proliferation. Linderalactone also inhibits the mitochondrial membrane potential, leading to cell lysis and death. This compound has been shown to have inhibitory properties against colon cancer cells in culture, as well as to induce apoptosis in malignant brain cells. The mechanism by which this compound induces apoptosis may be caspase-independent cell death.
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Chemische Eigenschaften
Molekulargewicht:244.29 g/mol
Formel:C15H16O3
Reinheit:Min. 95%
InChl:InChI=1S/C15H16O3/c1-9-4-3-5-11-7-13(18-15(11)16)14-10(2)8-17-12(14)6-9/h4,7-8,13H,3,5-6H2,1-2H3/b9-4-/t13-/m1/s1
InChI Key:InChIKey=LWCKQMHMTSRRAA-VVOKDJNJSA-N
SMILES:C/C1=C\CCC2=C[C@@H](OC2=O)c2c(C)coc2C1