(+)-Lactacystin

CAS: 133343-34-7

Ref. 3D-FL24826

Produktinformation

• Name: (+)-Lactacystin
• Synonyme: N-Acetyl-S-[(3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-D-prolyl]-L-cysteineLactacystin, (2R,3S,4R)-3-Hydroxy-2-[(1S)-1-Hydroxy-2-Methylpropyl]-4-Methyl-5-Oxo-2-Pyrrolidinecarboxy-N-Acetyl-L-Cysteine Thioester, 3S-Hydroxy-2R-(1-Hydroxy-2-Methylpropyl)-4R-Methyl-5-Oxo-2-Pyrrolidinecarboxylate-N-Acetyl-L-Cysteine, <span class="text-smallcaps">L</smallcap>-Cysteine, N-acetyl-S-[(3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-<smallcap>D</span>-prolyl]-, <span class="text-smallcaps">L</span>-Cysteine, N-acetyl-, (2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinecarboxylate (ester), <span class="text-smallcaps">L</span>-Cysteine, N-acetyl-, 3-hydroxy-2-(1-hydroxy-2-methylpropyl)-4-methyl-5-oxo-2-pyrrolidinecarboxylate (ester), [2R-[2α,2(S*),3α,4α]]-, Lactacystin (Native), Lactacystin, Streptomyces Sp, Lactacystin, Synthetic, N-Acetyl-S-[(2R,3S,4R)-3-Hydroxy-2-[(1S)-1-Hydroxy-2-Methylpropyl]-4-Methyl-5-Oxo-2-Pyrrolidinecarbonyl]-L-Cysteine, N-Acetyl-S-[(3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-<span class="text-smallcaps">D</smallcap>-prolyl]-<smallcap>L</span>-cysteine, N-acetyl-S-({(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)-L-cysteine, N-acetyl-S-({(2R,3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-3-methylbutyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)-L-cysteine, N-acetyl-S-({(3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)-L-cysteine
• CAS: 133343-34-7

Beschreibung

Lactacystin is a natural compound that belongs to the class of diketopiperazines. It has been shown to induce apoptosis in 3T3-L1 preadipocytes, HL-60 cells and myeloma cell lines. Lactacystin also inhibits mitochondrial membrane potential, leading to the release of cytochrome c from the mitochondria into the cytosol where it triggers an increase in pro-apoptotic protein Bax and a decrease in anti-apoptotic protein Bcl-2. This process leads to caspase activation and DNA fragmentation, resulting in cell death.

The following are examples of high quality product descriptions:

6-Fluoro-3-indoxyl-beta-D-galactopyranoside
Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It is the most active of the rif

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 376.43 g/mol
• Formel: C₁₅H₂₄N₂O₇S
• Reinheit: Min. 95%
• Farbe/Form: Powder