Letaxaban

CAS: 870262-90-1

Ref. 3D-FL24871

Produktinformation

• Name: Letaxaban
• Synonyme: 1-[1-[(2S)-3-[(6-chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-piperidinyl]tetrahydro-2(1H)-pyrimidinoneTAK 4421-[(2S)- 3-[(6-Chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-(tetrahydro-2-oxo-1(2H)-pyrimidinyl)piperidine

Beschreibung

Letaxaban is an anticoagulant drug that inhibits the enzyme thrombin by covalent binding. It is used in the treatment of deep vein thrombosis, pulmonary embolism and atrial fibrillation. Letaxaban also has a specific antidote for use in cases of overdose or suspected overdose. Letaxaban has been shown to have a synergistic effect with aspirin and clopidogrel, as well as with natural compounds such as coumarin derivatives and chemoattractant protein. The low-dose group showed improved pharmacokinetic properties compared with the high-dose group, which may be due to increased bioavailability and reduced degradation by cytochrome P450 enzymes.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 479.98 g/mol
• Formel: C₂₂H₂₆ClN₃O₅S
• Reinheit: Min. 95%