LY 404039

CAS: 635318-11-5

Ref. 3D-FL65070

Produktinformation

• Name: LY 404039
• Synonyme: Pomaglumetad, (1R,4S,5S,6S)-4-Amino-2-Thiabicyclo[3.1.0]Hexane-4,6-Dicarboxylic Acid 2,2-Dioxide (Ly 404039), (1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide, 2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, 4-amino-, 2,2-dioxide, (1R,4S,5S,6S)-, Ly 404039, Ly 404040
• CAS: 635318-11-5

Beschreibung

LY-404039 is a potent metabotropic glutamate receptor agonist with nanomolar affinity for group II receptors mGluR2 (Ki = 149 nM) and mGluR3 (Ki = 92 nM). It modulates glutamatergic activity in limbic and forebrain areas and has antipsychotic properties in animal studies. LY-404039 represents a potential new therapy for neurophysiatric disorders including schizophrenia, psychosis and anxiety.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 235.01506
• Formel: C₇H₉NO₆S
• Reinheit: Min. 95%
• Farbe/Form: Solid
• InChl: InChI=1S/C7H9NO6S/c8-7(6(11)12)1-15(13,14)4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2?,3?,4-,7-/m0/s1
• InChI Key: InChIKey=AVDUGNCTZRCAHH-NJTBGMRFSA-N
• SMILES: N[C@@]1(C(=O)O)CS(=O)(=O)[C@H]2C(C(=O)O)C21