ε-Maleimidocaproic acid-(2-nitro-4-sulfo)-phenyl ester·sodium salt

CAS: 101554-76-1

Ref. 3D-FM111177

Produktinformation

• Name: ε-Maleimidocaproic acid-(2-nitro-4-sulfo)-phenyl ester·sodium salt
• Synonyme: mal-sac-HNSA, N-Maleimido-6-aminocaproyl 1-hydroxy-2-nitro-4-benzenesulfonic acid ester, Mal-sac-hnsa, Benzenesulfonic acid, 4-((6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl)oxy)-3-nitro-, sodium salt, 1H-pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2-nitro-4-sulfophenyl ester, sodium salt (1:1)

Beschreibung

Epsilon-Maleimidocaproic acid-(2-nitro-4-sulfo)-phenyl ester·sodium salt (EMAP) is a crosslinker that belongs to the group of heterobifunctional reagents. It has been used to conjugate monoclonal antibodies with other molecules, such as toxins. EMAP is activated by the dianion generated by protonation of the nitro groups on the phenyl ring and reacts with free amines or thiols in proteins. EMAP can be used for labeling immunotoxins for diagnostic use, maximizing detection sensitivity, and crosslinking DNA molecules for use in molecular cloning experiments.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 434.35 g/mol
• Formel: C₁₆H₁₅N₂NaO₉S
• Reinheit: Min. 95%