L-Mimosine
CAS: 500-44-7
Ref. 3D-FM12108
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Produktinformation
- (S)-α-Amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionsaure
- (S)-α-amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid
- (αS)-α-Amino-3-hydroxy-4-oxo-1(4H)-pyridinepropanoic acid
- 1(4H)-Pyridinepropanoic acid, α-amino-3-hydroxy-4-oxo-, (S)-
- <span class="text-smallcaps">L</span>-Mimosine
- Leucaenine
- Leucaenol
- Leucenine
- Leucenol
- Mimosin
- Mehr Synonyme anzeigen
- Mimosine
- Nsc 69188
- acide (S)-α-amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionique
- acido (S)-α-amino-3-hidroxi-4-oxo-1(4H)-piridilpropionico
L-Mimosine is a polymerase chain inhibitor that binds to the β subunit of RNA polymerase and inhibits transcription. The L-mimosine has been found to have significant cytotoxicity in human osteosarcoma cells and skin cancer cells. L-Mimosine has also been shown to inhibit tumor progression in vivo. In addition, L-mimosine has been shown to significantly increase the expression of dopamine β hydroxylase, an enzyme that converts dopamine into norepinephrine, which is important for healthy skin function.
The kinetic data of L-mimosine was determined by measuring the inhibition of DNA synthesis following drug treatment. This data is represented as a percentage of control values and plotted against time.