6-Methoxy-1-benzofuran-3(2H)-one
CAS: 15832-09-4
Ref. 3D-FM123798
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Produktinformation
Name:
6-Methoxy-1-benzofuran-3(2H)-one
Synonyme:
- 3(2H)-benzofuranone
- 6-methoxy-
- 5-Fluoro-3-Benzofuranone
- 5-fluoro-1-benzofuran-3(2H)-one
Beschreibung:
6-Methoxy-1-benzofuran-3(2H)-one is a polymerization inhibitor that binds to tubulin and inhibits the polymerization of tubulin. This compound has shown high potency against cancer cells in vitro, including A549 cells, MCF7 cells, and MDA-MB231 cells. 6-Methoxy-1-benzofuran-3(2H)-one also has growth inhibitory activity on cancer cell lines at concentrations of 100 μmol/L or less. This active form is also an aliphatic compound. It can be synthesized from tetrahydrofuran (THF) using various methods such as Noyori coupling or aldol condensation. 6-Methoxy-1-benzofuran-3(2H)-one has been shown to inhibit the growth of cancer cells by binding to the microtubule network and inhibiting the polymerization of tubulin. The mechanism
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Marke:
Biosynth
Langzeitlagerung:
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Chemische Eigenschaften
Molekulargewicht:
164.16 g/mol
Formel:
C9H8O3
Reinheit:
Min. 95%
InChl:
InChI=1S/C9H8O3/c1-11-6-2-3-7-8(10)5-12-9(7)4-6/h2-4H,5H2,1H3
InChI Key:
InChIKey=BLLMRPOVMOPQKC-UHFFFAOYSA-N
SMILES:
COc1ccc2c(c1)OCC2=O
MDL:
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Flammpunkt:
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