4-Methyl-3-nitrobenzenesulfonyl chloride

CAS: 616-83-1

Ref. 3D-FM134326

Produktinformation

• Name: 4-Methyl-3-nitrobenzenesulfonyl chloride
• Synonyme: 4-Methyl-3-nitrobenzene-1-sulfonyl chloride
• Marke: Biosynth
• Beschreibung: 4-Methyl-3-nitrobenzenesulfonyl chloride (4MNBS) is a fungicide that inhibits the growth of fungi, such as Plasmodiophora brassicae, by inhibiting the enzyme dehydrogenase. 4MNBS has also been shown to inhibit mammalian pyridine nucleotide dehydrogenase and to have low toxicity in mammals. 4MNBS has been found to be an inhibitor of human cytochrome P450 isoforms CYP1A2, CYP2B6, and CYP3A4 with IC50 values ranging from 10 μM to 100 μM. 4MNBS was also shown to be a potent inhibitor of chloroplast dehydrogenases from cruciferous plants with IC50 values between 0.1 μM and 100 nM. This compound has low phytotoxicity and does not accumulate in the leaves of cruciferous plants at a concentration of 500 ppm or higher.

Chemische Eigenschaften

• Molekulargewicht: 235.65 g/mol
• Formel: C₇H₆ClNO₄S
• Reinheit: Min. 95%