Methyl 3-bromo-4-formylbenzoate

CAS: 90484-53-0

Ref. 3D-FM141288

Produktinformation

• Name: Methyl 3-bromo-4-formylbenzoate

Beschreibung

Methyl 3-bromo-4-formylbenzoate is a diastereoselective and efficient method for the synthesis of substituted aryl-substituted tetrahydroquinolines. This compound is prepared by reacting an aromatic aldehyde with methyl 4-formylbenzoate in the presence of base, followed by selective bromination of one of the two possible ortho methyl groups on the benzoic acid moiety. Methyl 3-bromo-4-formylbenzoate has been shown to yield high yields (up to 95%) when used as a substrate for cyclization reactions. The regioselectivity and stereochemistry of this reaction can be controlled by using different substituents on the aromatic ring.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 243.05 g/mol
• Formel: C₉H₇BrO₃
• Reinheit: Min. 95%
• InChl: InChI=1S/C9H7BrO3/c1-13-9(12)6-2-3-7(5-11)8(10)4-6/h2-5H,1H3
• InChI Key: InChIKey=OILDTPUIIUEPFL-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(C=O)c(Br)c1