3-Methyl-2,3-dihydroindole hydrochloride

CAS: 4375-15-9

Ref. 3D-FM155467

Produktinformation

• Name: 3-Methyl-2,3-dihydroindole hydrochloride
• Synonyme: 1H-Indole, 2,3-dihydro-3-methyl-, 2,3-Dihydro-3-methyl-1H-indole, 2,3-Dihydro-3-methylindole, 3-Methyl Indoline, 3-Methyl-2,3-Dihydroindole, 3-Methylindoline, 3-methyl-2,3-dihydroindole-HCl, Indoline, 3-methyl-, 3-Methyl-2,3-dihydro-1H-indole

Beschreibung

3-Methyl-2,3-dihydroindole hydrochloride is an ezh2 inhibitor. It is a chiral molecule that binds to the catalytic subunit of the enzyme histone H3 methyltransferase (EHMT1) and inhibits the transfer of methyl groups from S-adenosylmethionine to lysine residues in the DNA. The synthesis of this compound was achieved by a chemoenzymatic approach with a lipase as catalyst. This reaction system has been shown to be functional for the synthesis of molecules with different functional groups. 3-Methyl-2,3-dihydroindole hydrochloride has been reported to inhibit EHMT1 in living cells, which may lead to epigenetic changes in gene expression. The reaction time for this synthesis is about 30 minutes.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 169.65 g/mol
• Formel: C₉H₁₂ClN
• Reinheit: Min. 95%