4-Methyl-7H-pyrrolo[2,3-d]pyrimidine

CAS: 945950-37-8

Ref. 3D-FM158215

Produktinformation

• Name: 4-Methyl-7H-pyrrolo[2,3-d]pyrimidine
• CAS: 945950-37-8

Beschreibung

4-Methyl-7H-pyrrolo[2,3-d]pyrimidine is an anti-HIV drug that has been shown to have a potent anti-HCV activity in molecular modeling studies. The compound has been optimized for binding to the HCV NS5B RNA polymerase and the lead discovery step has been completed. 4-Methyl-7H-pyrrolo[2,3-d]pyrimidine is a ligand that binds to the C2' hydroxyl group of the nucleoside analogs and prevents them from being incorporated into the growing DNA chain. This leads to a halt in viral replication. The conformation of this molecule was determined by molecular modeling techniques and its amino group was bioisosterically replaced by a carbocyclic nucleoside.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 133.15 g/mol
• Formel: C₇H₇N₃
• Reinheit: Min. 95%