Produktinformation
- D-Mannose, 2-amino-2-deoxy-
- 2-Amino-2-deoxy-D-mannose
- Mannose, 2-amino-2-deoxy-, D-
- D-Mannosamine
Mannosamine (Man, 2-Amino-2-Deoxymannose) has the axial hydroxyl group at position 2 replaced by an amino group (Collins, 2006). Mannosamine has importance in the biosynthesis of sialic acids as they are synthesized by the condensation of D-mannosamine with pyruvic acid. Mannosamine has been found to have antitumor activity on human leukemia T-cell lines (Onoda, 1985). Mannosamine was also reported to inhibit glycosylphosphatidylinositol (GPI) synthesis in trypanosomes (Eckert, 1999).