Mureidomycin A

CAS: 114797-04-5

Ref. 3D-FM179085

Produktinformation

• Name: Mureidomycin A
• Synonyme: 3,5,8,11-Tetraazatetradecanoic acid, 13-amino-9-[[[[5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]amino]carbonyl]-14-(3-hydroxyphenyl)-2-[(3-hydroxyphenyl)methyl]-10,11-dimethyl-6-[2-(methylthio)ethyl]-4,7,12-trioxo-, stereoisomer, Butanamide, N-(((1-carboxy-2-(3-hydroxyphenyl)ethyl)amino)carbonyl)methionyl-N-((5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene)methyl)-N(sup 3)-(3-hydroxyphenylalanyl)-N(sup 3)-methyl-D-2,3-diamino-, Butanamide, N-[[[1-carboxy-2-(3-hydroxyphenyl)ethyl]amino]carbonyl]methionyl-N-[[5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene]methyl]-N³-(3-hydroxyphenylalanyl)-N³-methyl-<span class="text-smallcaps">D</span>-2,3-diamino-, Mrd A, N-{[(1S)-1-({2-amino-3-[(3-hydroxy-L-phenylalanyl)(methyl)amino]butanoyl}{(E)-[5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxydihydrofuran-2(3H)-ylidene]methyl}carbamoyl)-3-(methylsulfanyl)propyl]carbamoyl}-3-hydroxyphenylalanine
• CAS: 114797-04-5

Beschreibung

Mureidomycin A is a potent antimicrobial agent that inhibits the biosynthesis of uridine and ester linkages in peptidoglycan by attacking the hydroxyl group on C-1. It also has potent inhibitory activity against P. aeruginosa, which is a Gram-negative bacterium. Mureidomycin A was isolated from a mutant strain of Streptomyces sp. The alkynyl group found in this compound is thought to be responsible for its biological activity as it reacts with nucleophiles such as hydroxyl groups. Mureidomycin A can be used to study protein-protein interactions in cells and cell lysis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 840.9 g/mol
• Formel: C₃₈H₄₈N₈O₁₂S
• Reinheit: Min. 95%